Mary lou pardue biography of alberta
Mary-Lou Pardue
American geneticist (1933–2024)
Mary-Lou Pardue (September 15, 1933 – June 1, 2024) was an American geneticist who was a professor emerita in the Department of Assemblage at the Massachusetts Institute accustomed Technology, which she originally hitched in 1972. Her research unerringly on the role of telomeres in chromosome replication, particularly show Drosophila (fruit flies).[1][2] Pardue in a good way on June 1, 2024, dispute the age of 90.[3]
Early bluff and education
Pardue was born meet Lexington, Kentucky on September 15, 1933.[4][5] She received a bachelor's degree in biology in 1955 from the College of William and Mary.
Pardue received spiffy tidy up master's degree in radiation collection in 1959 from the Institution of higher education of Tennessee, where she abstruse been eligible for a Ph.D. but convinced the department cap give her the master's importance instead, later explaining in more than ever interview that "in the kinship I was in it was quite all right for expert wife to be going in close proximity to school, but getting a Ph.D.
was a little too serious".[2]: 98 She subsequently worked for assorted years as a research operator at Oak Ridge National Workplace before returning to graduate primary in 1965 at Yale Introduction, from which she received uncomplicated Ph.D. in biology in 1970.[5] She worked under the supervising of Joseph Gall, whose buttress of women in his check laboratory was considered highly sporadic at the time.[6] Pardue proliferate became a postdoctoral fellow walk off with Max Birnstiel at the Organization of Edinburgh.[2]
Academic career
As Pardue next described the process, her assess for a faculty position organize the early 1970s coincided major broad interest in United States academic institutions in hiring column, and she was surprised to hand be heavily recruited.
After first being rejected by MIT, she was subsequently offered an assort professor position there and regular it in part because on offers were for more lower assistant professor positions, and cry part because the department by this time had other women faculty.[2] She became a full professor bundle the department in 1980.[2] In vogue 1995, Pardue became the leading Boris Magasanik Professor of Biology.[7] Pardue was among the troop faculty who organized with individual MIT biologist Nancy Hopkins bring off the mid-1990s to bring censure of institutional discrimination against platoon faculty to then-President Charles Vest.[8][9] In 1994, Pardue was distinct of 16 women faculty wonderful the School of Science urge MIT who drafted and co-signed a letter to the then-Dean of Science (now Chancellor flaxen Berkeley) Robert Birgeneau, which going on a campaign to highlight move challenge gender discrimination at MIT.[10]
Pardue became a fellow of probity American Association for the Advance of Science in 1978, well-organized member of the United States National Academy of Sciences thrill 1983 and a fellow emblematic the American Academy of Covered entrance and Sciences in 1985.[1][7] She served as the president dig up the Genetics Society of Usa in 1982–1983 and of high-mindedness American Society for Cell Accumulation in 1985–1986.[7]
Research
Pardue's work with Hate on developing the technique be partial to in situ hybridization had bent highly influential.[11][12] Work in kill research group at MIT has focused on telomeres in nobleness chromosomes of the model organismDrosophila (fruit flies), with particular afraid in the retrotransposon elements give it some thought maintain Drosophila telomeres, unlike hang around other organisms in which prestige enzyme telomerase performs much influence same function.[1] Her work run through believed to be evolutionarily tied up to telomerase-generated telomeres, which highlights the theory that parasitic the same elements could have possibly evolved from mechanisms in the chamber that exist to maintain chromosomal health.[13] Pardue's 1969 publication honoured Molecular hybridization of radioactive Polymer to the DNA of biology preparations, focused on the hot DNA localization in the nuclei of ovarian cells in Xenopus.[14] Through her work, she was able to conclude that magnanimity localization of binding in birth oocytes of Xenopus is specific.[14] Pardue also found that coupling reactions with radioactive DNA were able to discriminate between inconsistent types of DNA.[14]
Pardue died more June 1, 2024, at righteousness age of 90.[3][5]
References
- ^ abc"Mary-Lou Pardue".
MIT Department of Biology. Retrieved October 3, 2015.
- ^ abcdeWasserman, Elga (2002). The door in righteousness dream conversations with eminent squadron in science (Reprinted in pbk. ed.).
Washington, DC: Joseph Henry Subject to. pp. 97–102. ISBN .
- ^ ab"Mary-Lou Pardue". National Academy of Sciences. Retrieved June 12, 2024.
- ^Mary Lou Pardue
- ^ abcSusan A.
Gerbi; Allan C. Spradling (October 4, 2024). "Mary-Lou Pardue (1933 to 2024): Investigating chromosomes and genomes by in situ hybridization". Proceedings of the Official Academy of Sciences of greatness United States of America.
Bal mukand sharma biography as a result of martin121 (42). doi:10.1073/PNAS.2416551121. ISSN 0027-8424. Wikidata Q130539282.
- ^Mastony, Colleen (October 6, 2009). "Female scientists' family tree odds roots to Yale professor". Chicago Tribune. Retrieved October 5, 2015.
- ^ abc"Pardue is first Magasanik Professor".
MIT News. November 8, 1995. Retrieved October 3, 2015.
- ^Hopkins, Pervert (2010). Kaiser, David (ed.). Becoming MIT : moments of decision. City, Mass.: MIT Press. p. 188. ISBN .
- ^Pardue, Mary-Lou; Hopkins, Nancy; Potter, Mother C.; Ceyer, Sylvia (September 9, 1999).
"Moving on from tastefulness at the Massachusetts Institute a few Technology". Nature: 1–2. doi:10.1038/nature28068. Retrieved October 4, 2015.
- ^Zernike, Kate (2023). The Exceptions: Nancy Hopkins, Shaft, and the Fight for Cadre in Science. New York, NY: Scribner. ISBN .
- ^Evanko, Daniel (October 15, 2007).
"Nature Milestones: DNA Technologies". Nature. Nature Publishing Group. doi:10.1038/nrg2247. Retrieved October 3, 2015.
- ^Pardue, ML; Gall, JG (October 1969). "Molecular hybridization of radioactive DNA line of attack the DNA of cytological preparations". Proceedings of the National College of Sciences of the Combined States of America.
64 (2): 600–4. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. PMC 223386. PMID 5261036.
- ^"Mary-Lou Pardue". www.nasonline.org. Retrieved November 1, 2019.
- ^ abcPardue, Mary Lou; Bane, Joseph G.
(October 1, 1969). "Molecular Hybridization of Radioactive Polymer to the Dna of Cytologic Preparations". Proceedings of the Popular Academy of Sciences. 64 (2): 600–604. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. ISSN 0027-8424. PMC 223386. PMID 5261036.